Otumfuo Osei Tutu II is the current Chancellor of KNUST. He is the Asantehene and a direct descendant of the founder of the Asante Kingdom, Osei Tutu I. He is well-educated and experienced and undoubtedly competently suited to be the Chancellor of KNUST. He is instrumental in the success and administration of the University.
On the 1st of October, 2010, Professor William Otoo Ellis was appointed as Vice Chancellor for a four year term to steer the affairs of this great institution by the Council of this University. He was inducted into office on the 2nd of October, 2010 and swore the oath of service and was formally outdoored to the University Community and to the rest of the general public.